WE HAVE PRESENT OUR NEW MEDICINE PRODUCTS

Andrey N. Belousov is Head of Laboratory Applied Nanotechnologies. 

Andrey Nikolayevich Belousov graduate from Kharkov Medical Institute in 1988. 

Doctor of Medicine degree on speciality - Anesthesiology and Intensive Care since 2004. 

The author new method of extracorporal hemocorrection using magnet-controlled sorbent (MCS-B).

The title dissertation: “Extracorporal hemocorrection using magnet-controlled sorbent in intensive therapy of intoxication syndromes in patients with hepatopancreatoduodenales diseases”

The author new medicine products – nanotechnology preparations based on magnetite particles (Fe3O4) of the size 6-12 nm:

- Micromage-B (peroral form of biologically active additive);

- Magnet-controlled  sorbent (MCS-B) for extracorporal detoxication of biological liquids (blood);

- Nanobiocorrector for intravenous application - ICNB (intracorporal nanosorbent). 

Nowadays nanotechnology as a new direction of science allows to develop therapeutic methods of the endogenous intoxication syndrome and to create a new class of biocompatible sorbents. The product of nanotechnology  is colloid magnetite particles (Fe3O4). Each magnetite particle is a subdomain elementary magnetite of a sphere shape. The presence of adsorption layer of colloid particles provide a high sorptive activity. 

The main biological action of magnet-controlled sorbent is directed to regulation of cell metabolism. Using magnet-controlled sorbent the method of extracorporal hemocorrection  on the whole is rather the method of effective and reliable way to activate natural processes of detoxication of organism, than the method of artificial detoxication. The systematic analysis revealed some peculiarities of system effect of the proposed method in the therapy of endogenous intoxication syndrome, conditioned by pathology of organs of hepatoduodenal and pancreatic zone. The system effect is in reducing the number and power of correlation among the elements of functional system of  patient’s organism that is transmitting it into a more economic mode of its functioning, and in cardinal destroying of pathogenetic matrix of correlation and forming to 98,7 % a new functional system. 

Some theoretical and experimental research made on the problem of application of magnet-controlled sorbent in clinical practice allows not only to make real improving of some known therapy of the syndrome of endogenous intoxication, but to achieve technical simplicity, safety of application and noticeably reduce the cost of medical treatment. The absence of contra-indication and incidental effects (haematic, haemodynamic, hormone, electrolytic, immune) creates real predisposition for using this method in intensive therapy of intoxication syndrome. The safety of the method was proved experimentally on practically healthy animals. During the period of application of the mentioned method on people not a single fatal case was registered.

Author a new program for estimation degree the severity of the patient. Based on previously developed a universal analytical system of the physiological state of the body (PHUAS) by the author proposed a new automatic program objective assessment of the severity of the patient's condition. Overall, the program can improve health of the population in terms of underfunding by the rapid and objective examination of a large quantity of people. Early on, with the help of the developed program is made possible among surveyed identify risk groups in the severity of general condition, to determine the optimal and effective options for prevention and treatment, saving time and money for the survey, use the data to correlate them with various factors influence of the environment (ecology, nutrition, addictions, drug, vaccine, methods of intensive therapy, pharmacotherapy, etc.).

The published more 160 scientific works on results application of nanotechnology preparation in experimental and practical medicine. He has got 7 patents for the invention, 21 collected scientific articles, 68 works in other publications and thesis of reports at international conferences and congresses, including 35 of them abroad (Rumania, Austria, Germany, Czech, Switzerland, Hungary, Denmark, Portugal, Italy, Canada, U.S.A., China, India, and others).

Author of the scientific film which focuses on the elaboration of artificial liver device and the development of a new direction in medicine – Nanotechnology.

Andrey Belousov was awarded Medical Diploma of Europe “An Honorary Scholar Europe” and R. Koch medal for the scientific achievements, development of a new direction in medicine and elaboration of new method of treatment by means preparations of nanotechnology in 2008. Member of the Ukrainian and Russian Society Nanotechnology.   

At now Andrey Belousov - the Head of Laboratory Applied Nanotechnologies in Ukraine, DM, Professor of Department Anesthesiology, Intensive Care, Transfusiology and Hematology Kharkov Medical Academy of Postgraduate Education.

Now we are seeking of some pharmacological firm for producing the preparation. We also hope for any scientific-practical cooperation and investments.

 

SOME RESULTS OF RESEARCH: 

  1. EXPERIMENTAL STUDY OF EFFECTS OF MAGNET-CONTROLLED SORBENT (Fe3O4) PARAMETERS OF ACID-BASE EQUILIBRIUM IN BLOOD AND PROCESSES OF GLYCOLYSIS IN ERYTHROCYTES
  2. ULTRASTRUCTURE OF HEPATIC CELLS IN RABBITS AFTER INJECTION OF MAGNETITE NANOPARTICLES
  3. INFLUENCE OF MAGNETITE NANOPARTICLES ON PERMEABILITY OF THE ERYTHROCYTES AND ERYPTOSIS. DISCOVERY OF THE NEW MECHANISMS FUNCTIONS OF CELLS
  4. EFFECT PRODUCES BY MAGNETIC FIELD INTENSITY OF MAGNETITE NANOPARTICLES ON BIOLOGICAL MEDIA IN LIVING ORGANISM
  5. EFFECTS OF MAGNETITE NANOPARTICLES ON MICROORGANISMS
  6. ROLE OF MICROMAGE-B IN THEORY OF DISCOVERING NEW KIND OF PATHOGENIC CAUSATIVE AGENTS OF HUMAN DISEASES
  7. APPLICATION OF PRODUCTS OF NANOTECHNOLOGY FOR "AN ARTIFICIAL LIVER" DEVICES CREATION
  8. The first steps on ways to opening the mechanisms cell regulation by nanotechnology preparations
  9. SPECTRUM OF APPLICATION MAGNETITE NANOPATICLES IN MEDICINE
  10. CONCEPTION OF USE OF MAGNETITE NANOPARTICLES AS CONTRASTING MEANS FOR MALIGNANT TUMORS AT MRI INVESTIGATION
  11. MECHANISMS CELL REGULATION BY COLLOID MAGNETITE PARTICLES (Fe3O4)
  12. INFLUENCE OF PHYSICAL FACTORS CAUSED BY MAGNETITE NANOPARTICLES ON DIFFERENT GROUPS OF MICROORGANISMS
  13. PROLONGATIONOF LIFE  PROCESSES IN THE ORGANISM BY THE  MAGNETITE NANOPARTICLES (MCS-B)

 


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